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You must take this medication exactly as directed or you will lower the amount of medicine you absorb into your body or you may cause your self harm. Take Actonel by mouth first thing in the morning, after you are up for the day. Do not eat or drink anything before you take Actonel. Swallow the tablets with a full glass (6 to 8 fluid ounces) of plain water. Do not take the tablets with any other drink. Do not chew or crush the tablet. After taking Actonel, do not eat breakfast, drink, or take any other medicines or vitamins for at least 30 minutes. Stand or sit up for at least 30 minutes after you take Actonel; do not lie down. Do not take your medicine more often than directed.

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